If you try to load a remote assembly using it’s path you’ll likely get a permission or operation exception. When using LoadFrom:Assembly a1 = Assembly.LoadFrom(file);I got this error. Could not load file or assembly or one of its dependencies. Operation is not supported. (Exception from HRESULT: 0x80131515) ![5126.image_5F00_thumb_5F00_2C51C4A6.png 5126.image_5F00_thumb_5F00_2C51C4A6.png](http://blogs.msdn.com/cfs-file.ashx/__key/communityserver-blogs-components-weblogfiles/00-00-00-40-51-metablogapi/5126.image_5F00_thumb_5F00_2C51C4A6.png)
Read more: Jon Gallant's Blog
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![5126.image_5F00_thumb_5F00_2C51C4A6.png 5126.image_5F00_thumb_5F00_2C51C4A6.png](http://blogs.msdn.com/cfs-file.ashx/__key/communityserver-blogs-components-weblogfiles/00-00-00-40-51-metablogapi/5126.image_5F00_thumb_5F00_2C51C4A6.png)
Read more: Jon Gallant's Blog
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